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Cervical Cancer in Focus
Cervical Cancer: Reducing the High Mortality Rate
The solution is two-fold, explains Michelle Davis, MD, of Harvard University and the Dana Farber Cancer Institute. Here's what she believes will make a difference. (0:56)
Cervical Cancer Screening: Is There a Problem?
Cervical biopsy diagnoses vary at multiple levels, including between laboratory facilities, pathologists, and colposcopists, according to a group of US-based researchers. These inconsistencies very likely contribute to overdiagnosis, underdiagnosis, and unnecessary treatment.
Gynecologic Oncology Trials: Patients with Limited English Less Likely to Participate
Accrual of patients with limited English proficiency to gynecologic oncology trials is approximately 3-fold lower than for fluent English speakers. Trial inclusion criteria, time constraints, and lack of translated study documents are important enrollment barriers.
Rethinking Cervical Cancer Screening Guidelines for Older Adults
A large population-based study showed that older patients with newly diagnosed cervical cancer were more likely to have late-stage disease and had a substantially lower survival rate compared to younger patients, suggesting a need to re-assess screening guidelines.
Vaginal Intraepithelial Neoplasia: Risk Factors After Hysterectomy for CIN
A small retrospective study points to advanced age as an independent risk factor for vaginal intraepithelial neoplasia after hysterectomy for cervical intraepithelial neoplasia. Laser vaporization may be the best management approach to reduce risks of further recurrence.
Q&A with Dr. Hunter Holt: The Impact of Being Uninsured or Covered by Medicaid on Advanced Cervical Cancer Diagnosis
How much does being uninsured or covered by Medicaid explain racial and ethnic disparities in the diagnosis of advanced-stage cervical cancer? Dr. Hunter discusses what he and his colleagues learned.
In Locally Recurrent or Persistent Cervical Cancer, Preoperative Lymph Node Metastasis Predicts Disease Recurrence
Recurrence rates for invasive cervical cancer are high following first-line treatment. The presence of lymph node metastasis predicts recurrence following salvage surgery for locally recurrent or persistent cervical cancer.
HPV-Negative Cervical Cancer Needs More Attention and Research
HPV-negative cervical cancer research and progress has been overshadowed by progress for HPV-positive cervical cancer. Gaps in knowledge regarding biologic characteristics, biomarkers, classification, models, and therapeutic targets need to be addressed.
Less Than Half of Patients with Recurrent or Metastatic Cervical Cancer Receive Second-Line Therapy Following Disease Progressions
Cervical cancer remains an important cause of cancer mortality in the United States, and treatment options remain limited. Less than half of women with r/mCC receive second-line therapy, and second-line therapeutic approaches are inconsistent.