Oncology/Hematology

News, opinions and meeting coverage in oncology/hematology.

Delaying Esophageal Cancer Surgery After Neoadjuvant CRT Fails in Trial

— Histological complete response rates no better and survival appears worse

A three-dimensional computed tomography scan of the neck showing mapping of a radiotherapy treatment

Latest in Oncology/Hematology

Large Study Eases Fears Over Zantac-Cancer Link

In multinational cohort, cancer incidence with pulled drug no different than other H2RAs

Sep 19, 2023
Could Cetuximab Maintenance Play a Role in RAS Wild-Type Metastatic CRC?

Strategy tied to better outcomes but fails to meet primary goal of phase II trial

Sep 18, 2023
FDA Approves JAK Inhibitor That Addresses Anemia in Myelofibrosis

In a phase III trial, momelotinib reduced anemia, constitutional symptoms, and splenomegaly

Sep 18, 2023
Non-Erosive GERD May Not Increase Risk of Esophageal Cancer

Study shows similar incidence rates to general population, unlike for those with erosive GERD

Sep 18, 2023
FDA Approves JAK Inhibitor That Addresses Anemia in Myelofibrosis

In a phase III trial, momelotinib reduced anemia, constitutional symptoms, and splenomegaly

Non-Erosive GERD May Not Increase Risk of Esophageal Cancer

Study shows similar incidence rates to general population, unlike for those with erosive GERD

Oncology/Hematology Case Studies

Patient's Colonoscopy Refusal Highlights Value of CRC Screening

Man with a first-degree relative with CRC initially only agreed to stool-based testing

A computer rendering of colorectal cancer.
What Caused a Man to Develop Friable Bleeding Nodules on His Arms and Hips?

The cause lies in a lengthy history of cancer treatment, confirmed by histopathology analysis

A photo composite of a man with arm sores.
Testicular Mass Serendipitously Found 12 Years After Prostate Cancer Dx

Consistently low PSA levels failed to signal metastasis

A photo of a senior man in hospital gown sitting in a wheelchair in a hospital hallway.

More in Oncology/Hematology

Is Being a Night Owl Unhealthy? CRC Screening Not Recommended Enough

Also in TTHealthWatch: CVD death and obesity

Sep 16, 2023
TTUHSC EL PASO HEALTHWATCH with their logo and photos of Rick Lange, MD, and Elizabeth Tracey
Weight-Loss Surgery Tied to Lower Blood Cancer Risk in Women

Consider surgery for primary prevention in people with obesity, researchers suggest

Sep 15, 2023
 A photo of a surgeon performing radiofrequency ablation
Cisplatin Shortage Eases; Air Pollution Linked to Breast Cancer; Pap Test Confusion

News, features, and commentary about cancer-related issues

Sep 15, 2023
Onco Break over a computer rendering of a cancer cell.
No 'Silver Bullet' for Generic Drug Shortage, House Members Told

A total of 301 drugs were in active shortage last year

Sep 14, 2023
A screenshot of Anna A. Eshoo speaking during this hearing.
Individualized SABR for Lung Tumors Yields Low Recurrence Rates

Strategy also results in low rates of severe toxic effects

Sep 14, 2023
A photo of a senior man receiving radiotherapy.
IMRT Best for Locally Advanced NSCLC, Study Suggests

Technique reduces risk of severe lung toxicity and radiation to the heart compared with 3D-CRT

Sep 13, 2023
WCLC over a photo of Suntec Singapore Convention & Exhibition Centre.
Early Oophorectomy May Accelerate Onset of Chronic Health Problems

Premenopausal bilateral oophorectomy tied to higher odds of arthritis, sleep apnea, and more

Sep 13, 2023
 A photo of a female and male surgeon performing gynecological surgery.
Novel Antibody-Drug Conjugate Shows Efficacy in Advanced EGFR-Mutated NSCLC

Confirmed responses reached 29.8% in heavily pretreated patients

Sep 13, 2023
WCLC over a photo of Suntec Singapore Convention & Exhibition Centre.
Study Questions Use of Aggressive Surgery in Early Mesothelioma

Randomized data suggest surgery increases risk of death by 28% over first 42 months

Sep 12, 2023
WCLC over a photo of Suntec Singapore Convention & Exhibition Centre.
Adding First-Line Chemo Boosts PFS in EGFR-Mutant Lung Cancer

Osimertinib plus chemotherapy improved PFS by nearly 9 months versus targeted agent alone

Sep 12, 2023
WCLC over a photo of Suntec Singapore Convention & Exhibition Centre.
Stem-Cell Mobilization Booster Wins FDA Approval for Multiple Myeloma

Motixafortide plus filgrastim increased adequate harvest rate from 9.5% to 67.5%

Sep 11, 2023
 FDA APPROVED motixafortide (Aphexda) for use with filgrastim (Neupogen) over a fluorescent image of human stem cells
FLT3 Inhibitor Improves AML Survival With or Without Stem-Cell Transplant

Best outcomes with transplantation, but non-transplant patients also benefited from quizartinib

Sep 11, 2023
SOHO over a photo of George R. Brown Convention Center in Houston, Texas.
First-Line Triplet Yields 'Striking' OS Result in Extensive-Stage SCLC

Median overall survival reached 19.3 months in Chinese trial

Sep 11, 2023
WCLC over a photo of Suntec Singapore Convention & Exhibition Centre.
Opt-Out Strategy Fails to Improve Breast Cancer Screening Completion Rates

Opt-out vs opt-in approach also resulted in more canceled referrals, increasing burden for staff

Sep 11, 2023
 A photo of a female radiologist and her mature patient during a mammogram
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